• Antibiotic use Human consumption patterns and effect on bacteria 

      Haugen, Pål (Doctoral thesis; Doktorgradsavhandling, 2015-03-17)
      Prescriptions of antibiotics in Norway, and the effect of antibiotics on bacteria were investigated. The aim was to describe the consumption of antibiotics through prescriptions to patients and address how antibiotics can favour bacterial resistance. Several methods were applied, multivariate statistics, quantile regression and mathematical modelling of experimental conditions aided in the investigations. ...
    • Antibiotics to outpatients in Norway—Assessing effect of latitude and municipality population size using quantile regression in a cross-sectional study. 

      Haugen, Pål; Simonsen, Gunnar Skov; Primicerio, Raul; Furberg, Anne-Sofie; Småbrekke, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-29)
      High antibiotic consumption rates are associated to high prevalence of antimicrobial resistance. Geographical differences in dispensing rates of antibiotics are frequently analysed using statistical methods addressing the central tendency of the data. Yet, examining extreme quantiles may be of equal or greater interest if the problem relates to the extremes of consumption rates, as is the case for ...
    • Gyrodactylus marinus infecting the gill filaments of farmed and wild Atlantic cod in Norway 

      Haugen, Pål (Mastergradsoppgave; Master thesis, 2009-05)
      Cod aquaculture is a rapidly expanding industry in Norway and with an increase of biomass in mariculture the concern for diseases spread to and from farmed populations of cod is increasing. The genus Gyrodactylus Nordmann, 1832 are parasitic monogeneans infecting teleost fish in marine and fresh water habitats worldwide. To investigate a possible problematic species of this genus the gill filaments ...
    • Parasite faunas of farmed cod and adjacent wild cod populations in Norway: a comparison 

      Heuch, Peter Andreas; Jansen, Peder Andreas; Hansen, Haakon; Sterud, Erik; MacKenzie, Ken; Haugen, Pål; Hemmingsen, Willy (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-07-14)
      Atlantic cod Gadus morhua L. is host to more than 120 parasite species. Background abundance of these parasite species on adjacent wild hosts determines the infection pressure on cod farmed in open pens. In 2006, 2007 and 2008, 343 cod were collected from 4 locations along the coast of Norway: Øksfjord, Kvarøy, Brønnøysund and Ålesund. Freshly killed wild local cod, wild migratory cod, hatchery-reared ...
    • A Trade-off between the Fitness Cost of Functional Integrases and Long-term stability of Integrons 

      Starikova, Irina; Harms, Klaus; Haugen, Pål; Lunde, Tracy Munthali; Primicerio, Raul; Samuelsen, Ørjan; Nielsen, Kaare Magne; Johnsen, Pål Jarle (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Horizontal gene transfer (HGT) plays a major role in bacterial microevolution as evident from the rapid emergence and spread of antimicrobial drug resistance. Few studies have however addressed the population dynamics of newly imported genetic elements after HGT. Here, we show that newly acquired class-1 integrons from Salmonella enterica serovar Typhimurium and Acinetobacter baumannii, free of ...